A genotype is a way to put the hepatitis C virus HCV into categories based on similar genes. HCV has six genotypes, labeled 1 through 6. There are also subtypes labeled with letters, for example, genotypes 1a and 1b. Most people are infected by a single, dominant genotype, but it is possible to have more than one at the same time called a mixed infection. Knowing your HCV genotype is important information that can help patients and doctors find the most effective treatment. All HCV genotypes cause the same amount of liver damage.
Genotypic Distribution of Hepatitis C Virus in Thailand and Southeast Asia
Like other viruses, hepatitis C has evolved into distinct subgroups, which has made the virus difficult to treat with a universal drug. Doctors recognize six major genotypes, although there may be as many as Because genotypes are the result of evolution, distinct types are often clustered in certain parts of the world and distributed elsewhere through migration. Genotypes 1, 2 and 3 are common in North America, but are also seen across the globe. Credit: MattZ90 for iStock via Thinkstock. Historically, patients with genotype 1 were the most difficult to treat, but that changed with the recent wave of new medicines called direct-acting antivirals. This new generation of drugs, the first of which was approved in , dramatically improved the odds for patients with genotype 1, and new drugs and drug combinations followed.
Possible New Hepatitis B Virus Genotype, Southeast Asia
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Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited.